Risk assessment of di(2-ethylhexyl) phthalate in the workplace

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Risk assessment of di(2-ethylhexyl) phthalate in the workplace

OBJECTIVES A hazard assessment of di(2-ethylhexyl) phthalate (DEHP), a commonly used workplace chemical, was conducted in order to protect the occupational health of workers. A literature review, consisting of both domestic and international references, examined the chemical management system, working environment, level of exposure, and possible associated risks. This information may be utilize...

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Chemical activity-based environmental risk analysis of the plasticizer di-ethylhexyl phthalate and its main metabolite mono-ethylhexyl phthalate.

The present study applies a chemical activity-based approach to: 1) evaluate environmental concentrations of di-ethylhexyl phthalate (DEHP; n = 23 651) and its metabolite mono-ethylhexyl phthalate (MEHP; n = 1232) in 16 environmental media from 1174 studies in the United States, Canada, Europe, and Asia, and in vivo toxicity data from 934 studies in 20 species, as well as in vitro biological ac...

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Di2-ethylhexyl phthalate disrupts thyroid hormone homeostasis through activating the Ras/Akt/TRHr pathway and inducing hepatic enzymes

Di(2-ethylhexyl) phthalate (DEHP), as a widespread environmental pollutant and an endocrine disruptor, can disturb the homeostasis of thyroid hormones (THs). In order to elucidate roles of the MAPK and PI3K/Akt pathways and hepatic enzymes in thyroid-disrupting effects of DEHP, Sprague-Dawley rats were dosed with DEHP by gavage for 30 consecutive days; Nthy-ori 3-1 cells were treated with DEHP ...

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Adsorption of Bis (2-ethylhexyl) Phthalate

The adsorption of Bis (2-ethylhexyl) phthalate (DEHP) on the carbon adsorbents (Chezacarb S and Chezacarb SH) and polymer adsorbent on basis of polypropylene with polyethylene (Reo Fb) was studied. Efficiency of DEHP adsorption (concentration DEHP to 10 g.L, concentration of the adsorbents 1.7 g.L) was more then 99.9 %. By the sample from groundwater was efficiency more as 99.7 % in the case of...

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The in vitro serum protein-binding characteristics of bis-(2-ethylhexyl) phthalate and its principal metabolite, mono-(2-ethylhexyl) phthalate.

The metabolism and toxicity of the ubiquitous plasticizer, bis-(2-ethylhexyl) phthalate (DEHP), and its principal metabolite, mono-(2-ethylhexyl) phthalate (MEHP), have been extensively investigated. In an attempt to understand their disposition in man, we studied the in vitro serum protein-binding characteristics of these compounds, using ultracentrifugation and agarose gel electrophoresis. Th...

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ژورنال

عنوان ژورنال: Environmental Health and Toxicology

سال: 2016

ISSN: 2233-6567

DOI: 10.5620/eht.e2016011